Have Questions About Early Detection?

Why Is Screening So Important?

Cancer mortalities have outpaced population growth for too long.

Between 1970 and 2022 cancer mortalities have nearly doubled. Early Detection, Inc. is declaring war on the following cancers:

Cancer TypeEstimated 2022 New Cases% Of All Cancers

These five cancers represent more than half of all cases.

What is the TF antigen?

Thomsen‐Friedenreich antigen (TF antigen) is a disaccharide that serves as a core 1 structure in O-linked glycosylation.

First described by Thomsen as a red blood cells antigen, later research determined it to be an oncofetal antigen. It is present in the body as a part of membrane transport proteins, usually masked by the immune system.

TF antigens are commonly demasked in cancer cells and expressed in up to 90% of carcinomas, making them a potential target for immunotherapy.

Are these screening tests safe?

Our tests are very safe and noninvasive. There is no radiation or blood draw required.

How is accuracy determined in testing?

Two components make up accuracy-Sensitivity and Specificity.

Sensitivity refers to how effectively the test identifies the marker from a group of people. For example, if 10 out of 100 people had the condition and the test found 9 of them, the test would have a 90% sensitivity, as it revealed 9/10. Sensitivity is the most important of the two components, as we do not want to miss people that have cancer.

Specificity refers to the percentage of correct negative results when patients did not have the condition. In our example above, 90 of the 100 people did not have the condition. If 82 of these 90 correctly tested negative for the TF antigen marker, then the Specificity would be 91% or 82/90. The false positive %, in this case, would be 9%, as 8/90 people tested positive for the marker that did not have the condition.

How long does it take to get the test results?

Obtaining the mucus sample from the various organs takes a minute or two from each site.

Once the mucus or fluid samples are obtained for each organ, then the tests themselves take approximately 15 minutes for the reagents to work and get the results.

When our point of care tests are launched, patients will be able to get the test results before they leave their physician's office. This makes it much easier for physicians and their patients to determine if further evaluation and or testing is indicated, and then to schedule any follow up appointments or testing.

How often should people be screened for cancer?

We recommend screening everyone for the biomarker TF antigen during their routine physical examination.